KYNU polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with KYNU polyclonal antibody (Cat # PAB29901).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with KYNU polyclonal antibody (Cat # PAB29901).
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Specification
Product Description
Rabbit polyclonal antibody raised against partial synthetic protein of human KYNU.
Immunogen
A synthetic peptide corresponding to amino acids 251-300 of human KYNU.
Sequence
LAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
Host
Rabbit
Theoretical MW (kDa)
52
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:250)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1X PBS , pH 7.4 (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C for up to one week. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with KYNU polyclonal antibody (Cat # PAB29901).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with KYNU polyclonal antibody (Cat # PAB29901). -
Gene Info — KYNU
Entrez GeneID
8942Protein Accession#
Q16719Gene Name
KYNU
Gene Alias
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Gene Description
kynureninase (L-kynurenine hydrolase)
Gene Ontology
HyperlinkGene Summary
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
l-kynurenine hydrolase
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Interactome
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Pathway
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Disease
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