KRT2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial synthetic protein of human KRT2.
Immunogen
A synthetic peptide corresponding to amino acids 351-400 of human KRT2.
Sequence
EVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELN
Host
Rabbit
Theoretical MW (kDa)
70
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:250)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1X PBS , pH 7.4 (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C for up to one week. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate with KRT2 polyclonal antibody (Cat # PAB29900).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human intestine and (B) human lung tissues with KRT2 polyclonal antibody (Cat # PAB29900). -
Gene Info — KRT2
Entrez GeneID
3849Protein Accession#
P35908Gene Name
KRT2
Gene Alias
KRT2A, KRT2E, KRTE, MGC116967, MGC116968
Gene Description
keratin 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Other Designations
epidermal ichthyosis bullosa of Siemens
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