ATRIP (phospho S224) polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane 1: Untreated 293 cell lysates, Lane 2: Synthesized peptide treated 293 cell lysates reacted with ATRIP (phospho S224) polyclonal antibody (Cat # PAB29644) at 1:500-1:3000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human colon carcinoma tissue reacted with ATRIP (phospho S224) polyclonal antibody (Cat # PAB29644) at 1:50-1:100 dilution. The picture on the right is treated with the synthesized peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human ATRIP.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S224 of human ATRIP.
Host
Rabbit
Theoretical MW (kDa)
86
Reactivity
Human
Specificity
ATRIP (phospho S224) polyclonal antibody detects endogenous levels of human ATRIP only when phosphorylated at serine 224.
Form
Liquid
Purification
Affinity chromatography
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:3000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: Untreated 293 cell lysates, Lane 2: Synthesized peptide treated 293 cell lysates reacted with ATRIP (phospho S224) polyclonal antibody (Cat # PAB29644) at 1:500-1:3000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human colon carcinoma tissue reacted with ATRIP (phospho S224) polyclonal antibody (Cat # PAB29644) at 1:50-1:100 dilution. The picture on the right is treated with the synthesized peptide. -
Gene Info — ATRIP
Entrez GeneID
84126Protein Accession#
Q8WXE1Gene Name
ATRIP
Gene Alias
DKFZp762J2115, FLJ12343, MGC20625, MGC21482, MGC26740
Gene Description
ATR interacting protein
Omim ID
606605Gene Ontology
HyperlinkGene Summary
The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Disease
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