PER2 (phospho S662) polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human PER2.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S662 of human PER2.
Host
Rabbit
Theoretical MW (kDa)
120
Reactivity
Human, Mouse
Specificity
PER2 (phospho S662) polyclonal antibody detects endogenous levels of human PER2 only when phosphorylated at serine 662.
Form
Liquid
Purification
Affinity chromatography
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:3000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: Untreated NIH/3T3 cell lysates, Lane 2: Synthesized peptide treated NIH/3T3 cell lysates reacted with PER2 (phospho S662) polyclonal antibody (Cat # PAB29636) at 1:500-1:3000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain tissue reacted with PER2 (phospho S662) polyclonal antibody (Cat # PAB29636) at 1:50-1:100 dilution. The picture on the right is treated with the synthesized peptide. -
Gene Info — PER2
Entrez GeneID
8864Protein Accession#
O15055Gene Name
PER2
Gene Alias
FASPS, KIAA0347
Gene Description
period homolog 2 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. [provided by RefSeq
Other Designations
period 2|period circadian protein 2|period, Drosophila, homolog of, 2
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Interactome
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Disease
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