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PKM (phospho S37) polyclonal antibody

  • Catalog # : PAB29620
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of human PKM.
  • Immunogen:
  • A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S37 of human PKM.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 60
  • Reactivity:
  • Human
  • Specificity:
  • PKM (phospho S37) polyclonal antibody detects endogenous level of PKM only when phosphorylated at serine 37.
  • Form:
  • Liquid
  • Purification:
  • Affinity Chromatography
  • Recommend Usage:
  • Immunofluorescence (1:100-1:200)
    Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of methanol-fixed MEF cells using PKM (phospho S37) polyclonal antibody (Cat# PAB29620) at 1:100-1:200 dilution.
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5315
  • Gene Name:
  • PKM2
  • Gene Alias:
  • CTHBP,MGC3932,OIP3,PK3,PKM,TCB,THBP1
  • Gene Description:
  • pyruvate kinase, muscle
  • Gene Summary:
  • This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • OPA-interacting protein 3,PK, muscle type,pyruvate kinase M2,thyroid hormone-binding protein, cytosolic
  • Interactome
  • Interactome
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