Western blot analysis of Lane 1: mouse brain tissue lysate preincubated with blocking peptide, Lane 2: mouse brain tissue lysate without blocking peptide by MAPT (phospho T181) polyclonal antibody (Cat# PAB29606) at 1:500-1:1000 dilution.
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
G protein beta1/gamma2 subunit-interacting factor 1,microtubule-associated protein tau, isoform 4