PDE4B polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human epididymis with PDE4B polyclonal antibody (Cat # PAB29528) shows strong cytoplasmic positivity with granular pattern in glandular cells at 1:50-1:200 dilution.
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human PDE4B.
Immunogen
Recombinant protein corresponding to human PDE4B.
Sequence
SGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human epididymis with PDE4B polyclonal antibody (Cat # PAB29528) shows strong cytoplasmic positivity with granular pattern in glandular cells at 1:50-1:200 dilution. -
Gene Info — PDE4B
Entrez GeneID
5142Gene Name
PDE4B
Gene Alias
DKFZp686F2182, DPDE4, MGC126529, PDE4B5, PDEIVB
Gene Description
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
Omim ID
600127Gene Ontology
HyperlinkGene Summary
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000010652|OTTHUMP00000010656|OTTHUMP00000046896|cAMP-specific 3',5'-cyclic phosphodiesterase 4B|cAMP-specific phosphodiesterase-4 B isoform|dunce-like phosphodiesterase E4|phosphodiesterase 4B, cAMP-specific|phosphodiesterase 4B, cAMP-specific (d
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com