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PDE4B polyclonal antibody

  • Catalog # : PAB29528
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant human PDE4B.
  • Immunogen:
  • Recombinant protein corresponding to human PDE4B.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human epididymis with PDE4B polyclonal antibody (Cat # PAB29528) shows strong cytoplasmic positivity with granular pattern in glandular cells at 1:50-1:200 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5142
  • Gene Name:
  • PDE4B
  • Gene Alias:
  • DKFZp686F2182,DPDE4,MGC126529,PDE4B5,PDEIVB
  • Gene Description:
  • phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
  • Gene Summary:
  • This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000010652,OTTHUMP00000010656,OTTHUMP00000046896,cAMP-specific 3',5'-cyclic phosphodiesterase 4B,cAMP-specific phosphodiesterase-4 B isoform,dunce-like phosphodiesterase E4,phosphodiesterase 4B, cAMP-specific,phosphodiesterase 4B, cAMP-specific (d
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