Products

Western Blot (Cell lysate)

Western Blot (Cell lysate) analysis of RT-4 cell lysate with FKBP2 polyclonal antibody (Cat# PAB29504) at 1:250 - 1:500 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thyroid gland with FKBP2 polyclonal antibody (Cat# PAB29504) shows moderate cytoplasmic positivity in glandular cells at 1:500 - 1:1000 dilution.

Immunofluorescence

Immunofluorescent staining of PC-3 cells with FKBP2 polyclonal antibody (Cat# PAB29504) under 1-4 ug/mL working concentration shows positivity in plasma membrane. Antibody staining is shown in green.

Entrez GeneID

2286

Protein Accession#

P26885

Gene Name

FKBP2

Gene Alias

FKBP-13, PPIase

Gene Description

FK506 binding protein 2, 13kDa

Omim ID

186946

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Other Designations

FK506 binding protein 2 (13kD)|FK506-binding protein 2 (13kD)|peptidyl-prolyl cis-trans isomerase|proline isomerase|rapamycin-binding protein