Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with COPB1 polyclonal antibody (Cat# PAB29484) shows cytoplasmic positivity in cells in seminiferus ducts at 1:20 - 1:50 dilution.
Immunofluorescent staining of RH-30 cells with COPB1 polyclonal antibody (Cat# PAB29484) under 1-4 ug/mL working concentration shows positivity in cytoplasm and the Golgi apparatus. Antibody staining is shown in green.
This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq
beta coat protein,coatomer protein complex, subunit beta