PELI3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with PELI3 polyclonal antibody (Cat# PAB29481) shows strong cytoplasmic positivity in Purkinje cells while additional nuclear membranous staining in cells in molecular layer.
Immunofluorescence
Immunofluorescent staining of A-431 cells with PELI3 polyclonal antibody (Cat# PAB29481) under 1-4 ug/mL working concentration shows positivity in vesicles and nucleus but excluded from the nucleoli. Antibody staining is shown in green.
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Specification
Product Description
PELI3 polyclonal antibody raised against recombinant human PELI3.
Immunogen
Recombinant protein corresponding to amino acids of human PELI3.
Sequence
RSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with PELI3 polyclonal antibody (Cat# PAB29481) shows strong cytoplasmic positivity in Purkinje cells while additional nuclear membranous staining in cells in molecular layer.Immunofluorescence
Immunofluorescent staining of A-431 cells with PELI3 polyclonal antibody (Cat# PAB29481) under 1-4 ug/mL working concentration shows positivity in vesicles and nucleus but excluded from the nucleoli. Antibody staining is shown in green. -
Gene Info — PELI3
Entrez GeneID
246330Protein Accession#
Q8N2H9Gene Name
PELI3
Gene Alias
MGC35521
Gene Description
pellino homolog 3 (Drosophila)
Omim ID
609827Gene Ontology
HyperlinkGene Summary
Toll-like receptors (TLRs; see MIM 603030) and IL1R (IL1R1; MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).[supplied by OMIM
Other Designations
pellino 3 alpha
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