SYNE2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with SYNE2 polyclonal antibody (Cat # PAB29410) shows strong nuclear membrane positivity in cells in tubules.
Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SYNE2 polyclonal antibody (Cat # PAB29410) at 1-4 ug/mL concentration shows positivity in nucleus and nuclear membrane.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human SYNE2.
Immunogen
Recombinant protein corresponding to human SYNE2.
Sequence
NVLNDAYENLTRYKEAVTRAVESITSLEAIIIPYRVDVGNPEESLEMPLRKQEELESTVARIQDLTEKLGMISSPEAKLQLQYTLQELVSKNSAMKEAFKAQETEAE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with SYNE2 polyclonal antibody (Cat # PAB29410) shows strong nuclear membrane positivity in cells in tubules.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SYNE2 polyclonal antibody (Cat # PAB29410) at 1-4 ug/mL concentration shows positivity in nucleus and nuclear membrane. -
Gene Info — SYNE2
Entrez GeneID
23224Gene Name
SYNE2
Gene Alias
DKFZp434H2235, DKFZp686E01115, DKFZp686H1931, FLJ11014, FLJ43727, FLJ45710, FLJ46790, KIAA1011, NUA, NUANCE, Nesprin-2, SYNE-2
Gene Description
spectrin repeat containing, nuclear envelope 2
Omim ID
608442Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
nesprin 2|nucleus and actin connecting element|synaptic nuclei expressed gene 2
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Interactome
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Disease
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