Western blot analysis of Lane 1: Human cell line RT-4 Lane 2: Human cell line U-251MG sp Lane 3: Human liver tissue Lane 4: Human tonsil tissue with GABPA polyclonal antibody (Cat # PAB29389) at 1:100-1:250 dilution.
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq
GA binding protein transcription factor, alpha subunit,OTTHUMP00000096114,human nuclear respiratory factor-2 subunit alpha,nuclear respiratory factor 2 alpha subunit