HIPK3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HIPK3.
Immunogen
A mixture of synthetic peptide (conjugated with KLH) corresponding to residues within 1100-1200 and 1134-1163 of human HIPK3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with HIPK3 polyclonal antibody (Cat # PAB2938) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma. -
Gene Info — HIPK3
Entrez GeneID
10114Protein Accession#
NP_005725;Q9H422Gene Name
HIPK3
Gene Alias
DYRK6, FIST3, PKY, YAK1
Gene Description
homeodomain interacting protein kinase 3
Omim ID
604424Gene Ontology
HyperlinkOther Designations
homeodomain-interacting protein kinase 3
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Interactome
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Disease
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Publication Reference
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Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation.
Lan HC, Li HJ, Lin G, Lai PY, Chung BC.
Molecular and Cellular Biology 2007 Jan; 27(6):2027.
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Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation.
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