Western blot analysis of Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) with HSPD1 polyclonal antibody (Cat # PAB29369) at 1:100-1:250 dilution.
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq
P60 lymphocyte protein,chaperonin,heat shock 60kD protein 1 (chaperonin),heat shock protein 65,mitochondrial heat shock 60kD protein 1 variant 1,mitochondrial matrix protein P1,short heat shock protein 60 Hsp60s1,spastic paraplegia 13 (autosomal dominant)