Immunohistochemical staining of human kidney with CD34 polyclonal antibody (Cat# PAB29333) shows strong cytoplasmic positivity in cells of tubules at 1:50-1:200 dilution.
Immunofluorescent staining of human cell line U-251 MG with CD34 polyclonal antibody (Cat# PAB29333) under 1-4 ug/mL working concentration shows positivity in cytoplasm and nucleus but excluded from the nucleoli.
The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq