TNFAIP3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung with TNFAIP3 polyclonal antibody (Cat# PAB29328) shows strong cytoplasmic positivity in macrophages.
Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with TNFAIP3 polyclonal antibody (Cat# PAB29328) under 1-4 ug/mL working concentration shows positivity in cytoplasm and centrosome.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human TNFAIP3.
Immunogen
Recombinant protein corresponding to amino acids of human TNFAIP3.
Sequence
QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKW
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung with TNFAIP3 polyclonal antibody (Cat# PAB29328) shows strong cytoplasmic positivity in macrophages.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with TNFAIP3 polyclonal antibody (Cat# PAB29328) under 1-4 ug/mL working concentration shows positivity in cytoplasm and centrosome. -
Gene Info — TNFAIP3
Entrez GeneID
7128Protein Accession#
P21580Gene Name
TNFAIP3
Gene Alias
A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
Gene Description
tumor necrosis factor, alpha-induced protein 3
Omim ID
191163Gene Ontology
HyperlinkGene Summary
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq
Other Designations
OTTHUMP00000017289|tumor necrosis factor inducible protein A20
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Interactome
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Disease
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