IGF2BP3 polyclonal antibody

Catalog # PAB29324

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Price

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Quantity

Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) with IGF2BP3 polyclonal antibody (Cat# PAB29324) at 1:100-1:250 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human placenta with IGF2BP3 polyclonal antibody (Cat# PAB29324) shows strong cytoplasmic and nuclear positivity in trophoblastic cell at 1:50-1:200 dilution.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescent staining of human cell line U-251 MG with IGF2BP3 polyclonal antibody (Cat# PAB29324) under 1-4 ug/mL working concentration shows positivity in cytoplasm.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant human IGF2BP3.

    Immunogen

    Recombinant protein corresponding to amino acids of human IGF2BP3.

    Sequence

    VVESCEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQ

    Host

    Rabbit

    Reactivity

    Human, Mouse, Rat

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:50-1:200)
    Western Blot (1:100-1:250)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) with IGF2BP3 polyclonal antibody (Cat# PAB29324) at 1:100-1:250 dilution.

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human placenta with IGF2BP3 polyclonal antibody (Cat# PAB29324) shows strong cytoplasmic and nuclear positivity in trophoblastic cell at 1:50-1:200 dilution.

    Immunofluorescence

    Immunofluorescent staining of human cell line U-251 MG with IGF2BP3 polyclonal antibody (Cat# PAB29324) under 1-4 ug/mL working concentration shows positivity in cytoplasm.
  • Gene Info — IGF2BP3

    Entrez GeneID

    10643

    Protein Accession#

    O00425

    Gene Name

    IGF2BP3

    Gene Alias

    DKFZp686F1078, IMP-3, IMP3, KOC1, VICKZ3

    Gene Description

    insulin-like growth factor 2 mRNA binding protein 3

    Omim ID

    608259

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq

    Other Designations

    IGF II mRNA binding protein 3|IGF-II mRNA-binding protein 3|KH domain containing protein overexpressed in cancer

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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