SOX6 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with SOX6 polyclonal antibody (Cat# PAB29321) shows strong nuclear positivity in myocytes.
Immunofluorescence
Immunofluorescent staining of human cell line CACO-2 with SOX6 polyclonal antibody (Cat# PAB29321) under 1-4 ug/mL working concentration shows positivity in nucleus but excluded from the nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human SOX6.
Immunogen
Recombinant protein corresponding to amino acids of human SOX6.
Sequence
TYKPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with SOX6 polyclonal antibody (Cat# PAB29321) shows strong nuclear positivity in myocytes.Immunofluorescence
Immunofluorescent staining of human cell line CACO-2 with SOX6 polyclonal antibody (Cat# PAB29321) under 1-4 ug/mL working concentration shows positivity in nucleus but excluded from the nucleoli. -
Gene Info — SOX6
Entrez GeneID
55553Protein Accession#
P35712Gene Name
SOX6
Gene Alias
HSSOX6
Gene Description
SRY (sex determining region Y)-box 6
Omim ID
607257Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants
Other Designations
SRY-box containing gene 6|Sox-6
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Interactome
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Disease
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