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IKBKG (phospho S376) polyclonal antibody

  • Catalog # : PAB29299
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IKBKG.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S376 of human IKBKG.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 48
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • IKBKG (phospho S376) polyclonal antibody detects endogenous levels of human IKBKG only when phosphorylated at serine 376.
  • Form:
  • Liquid
  • Purification:
  • Affinity Chromatography
  • Recommend Usage:
  • Immunohistochemistry (1:50~1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain tissue with IKBKG (phospho S376) polyclonal antibody (Cat# PAB29299) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8517
  • Gene Name:
  • IKBKG
  • Gene Alias:
  • AMCBX1,FIP-3,FIP3,Fip3p,IKK-gamma,IP,IP1,IP2,IPD2,NEMO
  • Gene Description:
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Gene Summary:
  • This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [supplied by RefSeq
  • Other Designations:
  • NFkappaB essential modulator,OTTHUMP00000026027,OTTHUMP00000026028,OTTHUMP00000026029,incontinentia pigmenti
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