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HRH1 (phospho S398) polyclonal antibody

  • Catalog # : PAB29279
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of human HRH1.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S398 of human HRH1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 55
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • HRH1 (phospho S398) polyclonal antibody detects endogenous levels of human HRH1 only when phosphorylated at serine 398.
  • Form:
  • Liquid
  • Purification:
  • Affinity Chromatography
  • Recommend Usage:
  • Immunofluorescence (1:100~1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of methanol-fixed HUVEC cells with HRH1 (phospho S398) polyclonal antibody (Cat# PAB29279) without blocking peptide (A) or preincubated with blocking peptide (B) at 1:100-1:200 dilution.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3269
  • Gene Name:
  • HRH1
  • Gene Alias:
  • H1-R,hisH1
  • Gene Description:
  • histamine receptor H1
  • Gene Summary:
  • Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000160133,histamine H(1) receptor,histamine receptor, subclass H1
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