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BAX (phospho T167) polyclonal antibody

  • Catalog # : PAB29272
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T167 of human BAX.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 21
  • Reactivity:
  • Human
  • Specificity:
  • BAX (phospho T167) polyclonal antibody detects endogenous levels of human BAX only when phosphorylated at threonine 167.
  • Form:
  • Liquid
  • Purification:
  • Affinity Chromatography
  • Recommend Usage:
  • Immunofluorescence (1:100~1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of methanol-fixed A-549 cells with BAX (phospho T167) polyclonal antibody (Cat# PAB29272) without blocking peptide (A) or preincubated with blocking peptide (B) at 1:100-1:200 dilution.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 581
  • Gene Name:
  • BAX
  • Gene Alias:
  • BCL2L4
  • Gene Description:
  • BCL2-associated X protein
  • Gene Summary:
  • The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
  • Other Designations:
  • apoptosis regulator BAX
  • Interactome
  • Interactome
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