Immunohistochemical staining of human brain tissue by KAT5 (phospho S90) polyclonal antibody (Cat # PAB29252) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
HIV-1 Tat interactive protein, 60kDa,K-acetyltransferase 5,Tat interacting protein, 60kDa,cPLA2 interacting protein