CLK2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of CLK2 polyclonal antibody (Cat # PAB2925) in HL-60 cell lysate. CLK2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CLK2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CLK2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CLK2 polyclonal antibody (Cat # PAB2925) in HL-60 cell lysate. CLK2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. -
Gene Info — CLK2
Entrez GeneID
1196Protein Accession#
P49760Gene Name
CLK2
Gene Alias
MGC61500, hCLK2
Gene Description
CDC-like kinase 2
Omim ID
602989Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation. [provided by RefSeq
Other Designations
CLK kinase|dual specificity protein kinase CLK2
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Interactome
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Publication Reference
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA,
PNAS 2002 Dec; 99(26):16899.
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Identification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher disease.
Winfield SL, Tayebi N, Martin BM, Ginns EI, Sidransky E.
Genome Research 1997 Oct; 7(10):1020.
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Activity and autophosphorylation of LAMMER protein kinases.
Lee K, Du C, Horn M, Rabinow L.
The Journal of Biological Chemistry 1996 Nov; 271(44):27299.
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
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