Western blot analysis of Lane 1: antigen-specific peptide treated 3T3 cells, Lane 2: 3T3 cells, Lane 3: A549 cells, Lane 4: Hela cells with CCNC (phospho S275) polyclonal antibody (Cat # PAB29241) at 1:500-1000 dilution.
Immunohistochemical staining of human breast carcinoma tissue by CCNC (phospho S275) polyclonal antibody (Cat # PAB29241) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq