CLDN5 (phospho Y217) polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue by CLDN5 (phospho Y217) polyclonal antibody (Cat # PAB29238) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CLDN5.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y217 of human CLDN5.
Host
Rabbit
Theoretical MW (kDa)
23
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of CLDN5 only when phosphorylated at tyrosine 217.
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue by CLDN5 (phospho Y217) polyclonal antibody (Cat # PAB29238) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution. -
Gene Info — CLDN5
Entrez GeneID
7122Protein Accession#
O00501Gene Name
CLDN5
Gene Alias
AWAL, BEC1, CPETRL1, TMVCF
Gene Description
claudin 5
Omim ID
602101Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
androgen withdrawal and apoptosis induced protein RVP1-like|transmembrane protein deleted in velocardiofacial syndrome
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Interactome
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Pathway
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Disease
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