Immunohistochemical staining of human brain tissue by CLDN5 (phospho Y217) polyclonal antibody (Cat # PAB29238) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
androgen withdrawal and apoptosis induced protein RVP1-like,transmembrane protein deleted in velocardiofacial syndrome