NTRK2 (phospho Y706/Y707) polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue by NTRK2 (phospho Y706/Y707) polyclonal antibody (Cat # PAB29222) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK2.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y706/Y707 of human NTRK2.
Host
Rabbit
Theoretical MW (kDa)
91
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of NTRK2 only when phosphorylated at tyrosine 706 and tyrosine 707.
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue by NTRK2 (phospho Y706/Y707) polyclonal antibody (Cat # PAB29222) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution. -
Gene Info — NTRK2
Entrez GeneID
4915Protein Accession#
Q16620Gene Name
NTRK2
Gene Alias
GP145-TrkB, TRKB
Gene Description
neurotrophic tyrosine kinase, receptor, type 2
Omim ID
600456Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BDNF/NT-3 growth factors receptor|OTTHUMP00000021573|OTTHUMP00000021574|OTTHUMP00000021575|OTTHUMP00000021576|OTTHUMP00000021577|tyrosine kinase receptor B
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