Western blot analysis of Lane 1: EGF treated 3T3 cells, Lane 2: antigen-specific peptide treated 3T3 cells with MERTK/TYRO3 (phospho Y749/681) polyclonal antibody (Cat # PAB29209) at 1:500-1000 dilution.
Immunohistochemical staining of human by MERTK/TYRO3 (phospho Y749/681) polyclonal antibody (Cat # PAB29209) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:500-1000 dilution.
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq