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MERTK/TYRO3 (phospho Y749/681) polyclonal antibody

  • Catalog # : PAB29209
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MERTK/TYRO3.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y749/681 of human MERTK/TYRO3.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 97
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects endogenous levels of MER/TYRO3 only when phosphorylated at tyrosine 749/681.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    Western Blot (1:500-1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Lane 1: EGF treated 3T3 cells, Lane 2: antigen-specific peptide treated 3T3 cells with MERTK/TYRO3 (phospho Y749/681) polyclonal antibody (Cat # PAB29209) at 1:500-1000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human by MERTK/TYRO3 (phospho Y749/681) polyclonal antibody (Cat # PAB29209) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:500-1000 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Protein Accession#:
  • Q12866;Q06418
  • Gene Name:
  • MERTK
  • Gene Alias:
  • MER,MGC133349,RP38,c-mer
  • Gene Description:
  • c-mer proto-oncogene tyrosine kinase
  • Gene Summary:
  • This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq
  • Other Designations:
  • MER receptor tyrosine kinase,STK kinase
  • Gene Information
  • Entrez GeneID:
  • 7301
  • Protein Accession#:
  • Q12866;Q06418
  • Gene Name:
  • TYRO3
  • Gene Alias:
  • BYK,Brt,Dtk,FLJ16467,RSE,Sky,Tif
  • Gene Description:
  • TYRO3 protein tyrosine kinase
  • Other Designations:
  • Tyro3 protein tyrosine kinase (sea-related receptor tyrosine kinase),tyrosine-protein kinase receptor TYRO3
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