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Retinol Binding Protein polyclonal antibody

  • Catalog # : PAB29196
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against native Human Retinol Binding Protein.
  • Immunogen:
  • Native purified human Retinol Binding Protein.
  • Host:
  • Chicken
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Recommend Usage:
  • ELISA (Capture: 1:200-1:500)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5947
  • Gene Name:
  • RBP1
  • Gene Alias:
  • CRABP-I,CRBP,CRBP1,CRBPI,RBPC
  • Gene Description:
  • retinol binding protein 1, cellular
  • Gene Summary:
  • This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • retinol-binding protein 1, cellular
  • Gene Information
  • Entrez GeneID:
  • 5948
  • Gene Name:
  • RBP2
  • Gene Alias:
  • CRABP-II,CRBP2,CRBPII,RBPC2
  • Gene Description:
  • retinol binding protein 2, cellular
  • Gene Summary:
  • RBP2 is an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. RBP2 may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. [provided by RefSeq
  • Other Designations:
  • retinol-binding protein 2, cellular
  • Gene Information
  • Entrez GeneID:
  • 5949
  • Gene Name:
  • RBP3
  • Gene Alias:
  • D10S64,D10S65,D10S66,IRBP,RBPI
  • Gene Description:
  • retinol binding protein 3, interstitial
  • Gene Summary:
  • Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019536,interphotoreceptor retinoid-binding protein,retinol-binding protein 3,retinol-binding protein 3, interstitial
  • Gene Information
  • Entrez GeneID:
  • 5950
  • Gene Name:
  • RBP4
  • Gene Alias:
  • -
  • Gene Description:
  • retinol binding protein 4, plasma
  • Gene Summary:
  • This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020114,OTTHUMP00000020116,retinol-binding protein 4, interstitial,retinol-binding protein 4, plasma
  • Gene Information
  • Gene Name:
  • RBP5
  • Gene Alias:
  • CRBP-III,CRBP3,CRBPIII
  • Gene Description:
  • retinol binding protein 5, cellular
  • Other Designations:
  • putative cellular retinol-binding protein CRBP III,retinol-binding protein 5, cellular
  • Gene Information
  • Gene Name:
  • RBP7
  • Gene Alias:
  • CRBP4,CRBPIV,MGC70641
  • Gene Description:
  • retinol binding protein 7, cellular
  • Gene Summary:
  • Due to its chemical instability and low solubility in aqueous solution, vitamin A requires cellular retinol-binding proteins (CRBPs), such as RBP7, for stability, internalization, intercellular transfer, homeostasis, and metabolism.[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000001729,putative cellular retinol-binding protein CRBP IV,retinoid binding protein 7
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