CDK10 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of CDK10 polyclonal antibody (Cat # PAB2909) in A-375 cell lysate.
CDK10 (arrow) was detected using CDK10 polyclonal antibody.
Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDK10 polyclonal antibody (Cat # PAB2909), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDK10.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDK10.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CDK10 polyclonal antibody (Cat # PAB2909) in A-375 cell lysate.
CDK10 (arrow) was detected using CDK10 polyclonal antibody.
Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDK10 polyclonal antibody (Cat # PAB2909), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. -
Gene Info — CDK10
Entrez GeneID
8558Protein Accession#
Q15131Gene Name
CDK10
Gene Alias
PISSLRE
Gene Description
cyclin-dependent kinase 10
Omim ID
603464Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CDC2-related protein kinase|cell division protein kinase 10|cyclin-dependent kinase (CDC2-like) 10|cyclin-dependent kinase related protein|serine/threonine protein kinase PISSLRE
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Interactome
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Publication Reference
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Cyclin-dependent kinases: engines, clocks, and microprocessors.
Morgan DO.
Annual Review of Cell and Developmental Biology 1997 Jan; 13:261.
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Cyclin-dependent kinases: engines, clocks, and microprocessors.
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