PRNP polyclonal antibody
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Specification
Product Description
Chicken polyclonal antibody raised against recombinant Human PRNP.
Immunogen
Recombinant fragment of human PRNP protein emulsified with Freund's adjuvant.
Host
Chicken
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgY
Quality Control Testing
Immunocytochemistry
PRNP polyclonal antibody (Cat # PAB29089) was analyzed by immunocytochemistry (1:1000 dilution).
Cultured fibroblast cells transiently transfected with plasmid encoding PRNP cDNA.Recommend Usage
Immunocytochemistry(1:1000-1:5000)
Immunohistochemistry(1:1000-1:5000)
Western Blot(1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C and avoid from light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunocytochemistry
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Gene Info — PRNP
Entrez GeneID
5621Gene Name
PRNP
Gene Alias
ASCR, CD230, CJD, GSS, MGC26679, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, prion
Gene Description
prion protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
CD230 antigen|OTTHUMP00000030162|OTTHUMP00000030163|major prion protein|p27-30|prion protein PrP|prion-related protein
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Interactome
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