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NEFL polyclonal antibody

  • Catalog # : PAB29082
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against recombinant Human NEFL.
  • Immunogen:
  • Three different KLH-conjugated synthetic peptides corresponding to different regions of NEFL gene product, shared between the human (P07196, NCBI) and mouse (P08551, NCBI) protein sequences.
  • Host:
  • Chicken
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Quality Control Testing:
  • Immunocytochemistry

    QC Testing of PAB29082
    Immunocytological staining of NEFL polyclonal antibody (Cat # PAB29082) (at a dilution of 1:2000).
    Positively stained axons in the cerebellar white matter of an adult mouse.
  • Recommend Usage:
  • Immunocytochemistry(1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.2% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C and avoid from light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 4747
  • Gene Name:
  • NEFL
  • Gene Alias:
  • CMT1F,CMT2E,FLJ53642,NF-L,NF68,NFL
  • Gene Description:
  • neurofilament, light polypeptide
  • Gene Summary:
  • Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq
  • Other Designations:
  • light molecular weight neurofilament protein,neurofilament protein, light chain,neurofilament subunit NF-L,neurofilament triplet L protein,neurofilament, light polypeptide 68kDa,neurofilament-light
  • Gene Information
  • Gene Name:
  • Nefl
  • Gene Alias:
  • AI847934,CMT2E,NF-L,NF68,Nfl
  • Gene Description:
  • neurofilament, light polypeptide
  • Other Designations:
  • OTTMUSP00000017610,neurofilament protein L
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