NEFL polyclonal antibody
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Immunocytological staining of NEFL polyclonal antibody (Cat # PAB29082) (at a dilution of 1:2000).
Positively stained axons in the cerebellar white matter of an adult mouse.
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Specification
Product Description
Chicken polyclonal antibody raised against recombinant Human NEFL.
Immunogen
Three different KLH-conjugated synthetic peptides corresponding to different regions of NEFL gene product, shared between the human (P07196, NCBI) and mouse (P08551, NCBI) protein sequences.
Host
Chicken
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgY
Quality Control Testing
Immunocytochemistry
Immunocytological staining of NEFL polyclonal antibody (Cat # PAB29082) (at a dilution of 1:2000).
Positively stained axons in the cerebellar white matter of an adult mouse.Recommend Usage
Immunocytochemistry(1:1000-1:2000)
Immunohistochemistry(1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.2% BSA, 0.02% sodium azide)
Storage Instruction
Store at 4°C and avoid from light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunocytochemistry
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Gene Info — NEFL
Entrez GeneID
4747Protein Accession#
P07196Gene Name
NEFL
Gene Alias
CMT1F, CMT2E, FLJ53642, NF-L, NF68, NFL
Gene Description
neurofilament, light polypeptide
Gene Ontology
HyperlinkGene Summary
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq
Other Designations
light molecular weight neurofilament protein|neurofilament protein, light chain|neurofilament subunit NF-L|neurofilament triplet L protein|neurofilament, light polypeptide 68kDa|neurofilament-light
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Gene Info — Nefl
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Interactome
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Pathway
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Disease
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