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Last updated: 2016/12/11

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MBP polyclonal antibody

  • Catalog # : PAB29078
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against recombinant Human MBP.
  • Immunogen:
  • A KLH-conjugated synthetic peptide shared between the human (NP_002376, NCBI) and mouse (NP_034907, NCBI) sequences.
  • Host:
  • Chicken
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Quality Control Testing:
  • Immunocytochemistry

    QC Testing of PAB29078
    Immunocytological staining of MBP polyclonal antibody (Cat # PAB29078) (at a concentration of 3 ug/mL).
    MBP-positive myelin (red) in cortical white matter from a GFP-expressing transgenic adult mouse.
  • Recommend Usage:
  • Immunocytochemistry(1:1000-1:2000)
    Immunohistochemistry(1:1000-1:2000)
    Western Blot(1:2000-1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C and avoid from light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunocytochemistry
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 4155
  • Gene Name:
  • MBP
  • Gene Alias:
  • MGC99675
  • Gene Description:
  • myelin basic protein
  • Gene Summary:
  • The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq
  • Other Designations:
  • Golli-mbp,OTTHUMP00000174383,OTTHUMP00000174384,OTTHUMP00000174385,OTTHUMP00000174386
  • Gene Information
  • Gene Name:
  • Mbp
  • Gene Alias:
  • C76307,Hmbpr,R75289,golli-mbp,mld,shi
  • Gene Description:
  • myelin basic protein
  • Other Designations:
  • Golli-mbp,OTTMUSP00000017514,OTTMUSP00000017515,myelin deficient,shiverer
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