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GRM3 polyclonal antibody

  • Catalog # : PAB29071
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against recombinant Human GRM3.
  • Immunogen:
  • A KLH-conjugated synthetic peptide corresponding to a unique sequence within GRM3 gene product, shared between the human (Q14832.2, NCBI) and mouse (Q9QYS2.1, NCBI) sequences.
  • Host:
  • Chicken
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Quality Control Testing:
  • Immunocytochemistry

    QC Testing of PAB29071
    GRM3 polyclonal antibody (Cat # PAB29071) was validated by immunocytological staining (at a concentration of 1 ug/mL).
    GRM3-staining of pyramidal neurons in the hippocampal formation of an adult mouse brain (red). Green staining is GFP-immunoreactivity for a subpopulation of cortical neurons.
  • Recommend Usage:
  • Immunocytochemistry(1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C and avoid from light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 2913
  • Gene Name:
  • GRM3
  • Gene Alias:
  • Gene Description:
  • glutamate receptor, metabotropic 3
  • Gene Summary:
  • L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq
  • Other Designations:
  • glutamate metabotropic receptor 3
  • Gene Information
  • Gene Name:
  • Grm3
  • Gene Alias:
  • 0710001G23Rik,Gprc1c,mGlu3,mGluR3
  • Gene Description:
  • glutamate receptor, metabotropic 3
  • Other Designations:
  • G protein-coupled receptor, family C, group 1, member C
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