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CHAT polyclonal antibody

  • Catalog # : PAB29065
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against recombinant Human CHAT.
  • Immunogen:
  • A KLH-conjugated synthetic peptide corresponding to a region of CHAT gene product shared between the human (P_066264, NCBI) and mouse (Q03059, NCBI) sequences.
  • Host:
  • Chicken
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Quality Control Testing:
  • Immunocytochemistry

    QC Testing of PAB29065
    CHAT polyclonal antibody (Cat # PAB29065) was analyzed by immunocytological staining (at a concentration of 3 ug/mL) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution) as the secondary reagent.
    CHAT-positive neurons (red) in the neostriatum of a GFP-expressing transgenic mouse.
  • Recommend Usage:
  • Immunocytochemistry(1:1000-1:2000)
    Immunohistochemistry(1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C and avoid from light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 1103
  • Gene Name:
  • CHAT
  • Gene Alias:
  • CMS1A,CMS1A2
  • Gene Description:
  • choline acetyltransferase
  • Gene Summary:
  • This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019583,OTTHUMP00000019584,acetyl CoA:choline O-acetyltransferase
  • Gene Information
  • Gene Name:
  • Chat
  • Gene Alias:
  • B230380D24Rik
  • Gene Description:
  • choline acetyltransferase
  • Other Designations:
  • -
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