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Last updated: 2016/10/23

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APP polyclonal antibody

  • Catalog # : PAB29064
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against recombinant APP.
  • Immunogen:
  • A KLH-conjugated synthetic peptide corresponding to residues 1-17 of the amyloid-beta peptide.
  • Sequence:
  • Host:
  • Chicken
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Quality Control Testing:
  • Immunohistochemistry

    QC Testing of PAB29064
    APP polyclonal antibody (Cat # PAB29064) was analyzed by immunohistochemical staining at a concentration of 3 ug/mL using fluorescein-labeled goat anti-chicken IgY at 1:500 dilution or HRP-labeled goat anti-chicken IgY at 1:2000 dilution as the secondary reagent.
  • Recommend Usage:
  • Immunocytochemistry
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C and avoid from light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 351
  • Gene Name:
  • APP
  • Gene Alias:
  • Gene Description:
  • amyloid beta (A4) precursor protein
  • Gene Summary:
  • This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • A4 amyloid protein,amyloid beta A4 protein,amyloid-beta protein,beta-amyloid peptide,cerebral vascular amyloid peptide,peptidase nexin-II,protease nexin-II
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  • Interactome
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