NXF3 polyclonal antibody
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More Files
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Immunohistochemistry
Immunohistochemical staining of human testis with NXF3 polyclonal antibody (Cat # PAB28740) shows strong nuclear and cytoplasmic positivity in cells in seminiferus ducts, Leydig cells expressed moderate cytoplasmic staining at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NXF3.
Immunogen
Recombinant protein corresponding to amino acids of human NXF3.
Sequence
NPAGIPHFVHRELKSEKVEQIKLAMNQQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAASLDVHEENIPTVMSAGEMDKWKGIEPGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human testis with NXF3 polyclonal antibody (Cat # PAB28740) shows strong nuclear and cytoplasmic positivity in cells in seminiferus ducts, Leydig cells expressed moderate cytoplasmic staining at 1:50-1:200 dilution. -
Gene Info — NXF3
Entrez GeneID
56000Gene Name
NXF3
Gene Alias
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Gene Description
nuclear RNA export factor 3
Omim ID
300316Gene Ontology
HyperlinkGene Summary
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq
Other Designations
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