FANCB polyclonal antibody
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More Files
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Western Blot
Western blot analysis of human cell line RT-4 with FANCB polyclonal antibody (Cat # PAB28737).
Immunohistochemistry
Immunohistochemical staining of human pancreas with FANCB polyclonal antibody (Cat # PAB28737) shows strong cytoplasmic positivity in exocrine glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant FANCB.
Immunogen
Recombinant protein corresponding to amino acids of human FANCB.
Sequence
DSLNSDCLTSFKITDLGKINYSSEPSDCNEDDLFEDKQENRYLVVPPLETGLKVCFSSFRELRQHLLLKEKIISKSYKALINLVQGKDDNTSSAEEKECLVPLCGEEENSVHILDEKLSDNFQDSEQLVEKIWY
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of human cell line RT-4 with FANCB polyclonal antibody (Cat # PAB28737).Immunohistochemistry
Immunohistochemical staining of human pancreas with FANCB polyclonal antibody (Cat # PAB28737) shows strong cytoplasmic positivity in exocrine glandular cells. -
Gene Info — FANCB
Entrez GeneID
2187Gene Name
FANCB
Gene Alias
FA2, FAAP90, FAAP95, FAB, FACB
Gene Description
Fanconi anemia, complementation group B
Gene Ontology
HyperlinkGene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq
Other Designations
Fanconi anemia complementation group B|OTTHUMP00000022953|type 2 Fanconi pancytopenia
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Interactome
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Disease
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