Western blot analysis of Lane 1: Human cell line RT-4, Lane 2: Human cell line U-251MG sp, Lane 3: Human cell line A-431, Lane 4: Human liver tissue, Lane5: Human tonsil tissue with NDRG2 polyclonal antibody (Cat # PAB28730) at 1:2500-1:5000 dilution.
Immunohistochemical staining of human salivary gland with NDRG2 polyclonal antibody (Cat # PAB28730) shows strong cytoplasmic positivity in glandular cells at 1:2500-1:5000 dilution.
Immunofluorescent staining of human cell line U-251MG with NDRG2 polyclonal antibody (Cat # PAB28730) at 1-4 ug/mL shows positivity in nucleus but not nucleoli, cytoplasm and centrosome.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
N-myc downstream regulator 2,N-myc downstream-regulated gene 2,NDR1-related protein NDR2,OTTHUMP00000164407,cytoplasmic protein Ndr1,syld709613 protein