MAPK4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAPK4.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 537-566 at C-terminus of human MAPK4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MAPK4 polyclonal antibody (Cat # PAB2872) in Jurkat cell lysate (35 ug/lane). MAPK4 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — MAPK4
Entrez GeneID
5596Protein Accession#
NP_002738;Q0VG04Gene Name
MAPK4
Gene Alias
ERK3, Erk4, PRKM4, p63MAPK
Gene Description
mitogen-activated protein kinase 4
Omim ID
176949Gene Ontology
HyperlinkGene Summary
Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets. [provided by RefSeq
Other Designations
Erk3-related
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Interactome
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Pathway
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Publication Reference
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Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling.
Lerner-Marmarosh N, Miralem T, Gibbs PE, Maines MD.
PNAS 2008 May; 105(19):6870.
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Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.
Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M.
The Journal of Biological Chemistry 2006 Sep; 281(46):35511.
Application:WB, Mouse, MEF cells.
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Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling.
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