NLGN3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NLGN3.
Immunogen
Recombinant protein corresponding to amino acids of human NLGN3.
Sequence
APAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTED
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate)
Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells)
with NLGN3 polyclonal antibody (Cat # PAB28709).Immunohistochemistry
Immunohistochemical staining of human cerebellum with NLGN3 polyclonal antibody (Cat # PAB28709) show scytoplasmic positivity in purkinje cells and in cells of granular layer. -
Gene Info — NLGN3
Entrez GeneID
54413Gene Name
NLGN3
Gene Alias
ASPGX1, AUTSX1, HNL3, KIAA1480
Gene Description
neuroligin 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but their full length sequences have not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000023498
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Interactome
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Disease
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