SKAP1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with SKAP1 polyclonal antibody (Cat # PAB28622) shows moderate cytoplasmic positivity.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with SKAP1 polyclonal antibody (Cat # PAB28622) at 1-4 ug/ml shows positivity in nucleus & cytoplasm.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SKAP1.
Immunogen
Recombinant protein corresponding to amino acids of human SKAP1.
Sequence
SLTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGDL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with SKAP1 polyclonal antibody (Cat # PAB28622) shows moderate cytoplasmic positivity.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with SKAP1 polyclonal antibody (Cat # PAB28622) at 1-4 ug/ml shows positivity in nucleus & cytoplasm. -
Gene Info — SKAP1
Entrez GeneID
8631Gene Name
SKAP1
Gene Alias
SCAP1, SKAP55
Gene Description
src kinase associated phosphoprotein 1
Omim ID
604969Gene Ontology
HyperlinkGene Summary
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq
Other Designations
src family associated phosphoprotein 1|src kinase-associated phosphoprotein of 55 kDa
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Interactome
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Disease
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