OPHN1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with OPHN1 polyclonal antibody (Cat # PAB28610) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant OPHN1.
Immunogen
Recombinant protein corresponding to amino acids of human OPHN1.
Sequence
RVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHQTPNGTITSSIEPPKPPQHPKLPIQRSGETDPGRKSPSRPILDGKLEPCPEVDVGKLVSRLQDGGTKITPK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with OPHN1 polyclonal antibody (Cat # PAB28610) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution. -
Gene Info — OPHN1
Entrez GeneID
4983Protein Accession#
O60890Gene Name
OPHN1
Gene Alias
MRX60, OPN1
Gene Description
oligophrenin 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism. [provided by RefSeq
Other Designations
OTTHUMP00000023451|mental retardation, X-linked 60|oligophrenin-1, Rho-GTPase activating protein
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Interactome
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Disease
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