Products

Western Blot (Transfected lysate)

Western blot analysis of SPAG9 polyclonal antibody (Cat # PAB2861).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPAG9 (N-term) gene (Lane 2) (Origene Technologies).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Formalin-fixed and paraffin-embedded human testisreacted with SPAG9 polyclonal antibody (Cat # PAB2861), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Entrez GeneID

9043

Protein Accession#

NP_003962;O60271

Gene Name

SPAG9

Gene Alias

FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6

Gene Description

sperm associated antigen 9

Omim ID

605430

Gene Ontology

Hyperlink

Gene Summary

Extracellular signals are transduced into cells through mitogen-activated protein kinases. The structural organization of these kinases into specific signaling domains is facilitated by scaffolding proteins involved in closely tethering different kinases so that successive phosphorylation events can occur. The protein encoded by this gene is a scaffolding protein that brings together mitogen-activated protein kinases and their transcription factor targets for the activation of specific signaling pathways. This gene which is abundantly expressed in testicular haploid germ cells encodes a protein that is recognized by sperm-agglutinating antibodies and implicated in infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Other Designations

HLC-4 protein|JNK interacting protein|JNK-associated leucine-zipper protein|JNK/SAPK-associated protein|Max-binding protein|c-Jun NH2-terminal kinase-associated leucine zipper protein|lung cancer oncogene 4|proliferation-inducing gene 6|sperm specific pro