CNTNAP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate); Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with CNTNAP2 polyclonal antibody (Cat#PAB28596).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with CNTNAP2 polyclonal antibody (Cat#PAB28596) shows strong cytoplasmic positivity in neuronal cells and distinct staining of neuropil.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CNTNAP2.
Immunogen
Recombinant protein corresponding to amino acids of human CNTNAP2.
Sequence
CNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:100-1:250)
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate); Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with CNTNAP2 polyclonal antibody (Cat#PAB28596).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with CNTNAP2 polyclonal antibody (Cat#PAB28596) shows strong cytoplasmic positivity in neuronal cells and distinct staining of neuropil. -
Gene Info — CNTNAP2
Entrez GeneID
26047Protein Accession#
B7Z1Y6Gene Name
CNTNAP2
Gene Alias
AUTS15, CASPR2, CDFE, DKFZp781D1846, NRXN4
Gene Description
contactin associated protein-like 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness. [provided by RefSeq
Other Designations
cell recognition molecule Caspr2|contactin-associated protein 2|homolog of Drosophila neurexin IV
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Interactome
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Pathway
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Disease
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