LNX1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant LNX1.
Immunogen
Recombinant protein corresponding to human LNX1.
Sequence
QLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVEL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human prostate with LNX1 polyclonal antibody (Cat # PAB28580) shows moderate cytoplasmic and membranous positivity in glandular cells. Retrieval method: HIER pH6 -
Gene Info — LNX1
Entrez GeneID
84708Protein Accession#
Q8TBB1Gene Name
LNX1
Gene Alias
LNX, MPDZ, PDZRN2
Gene Description
ligand of numb-protein X 1
Omim ID
609732Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000128294|PDZ domain-containing ring finger protein 2|multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX
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