NCF2 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: A-431, Lane 4: Liver, Lane 5: Tonsil with NCF2 polyclonal antibody (PAB28551).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with NCF2 polyclonal antibody (Cat # PAB28551) shows strong cytoplasmic positivity in bone marrow poietic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NCF2.
Immunogen
Recombinant protein corresponding to amino acids of recombinant NCF2.
Sequence
QEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:200-1:500)
Western Blot(1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: A-431, Lane 4: Liver, Lane 5: Tonsil with NCF2 polyclonal antibody (PAB28551).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with NCF2 polyclonal antibody (Cat # PAB28551) shows strong cytoplasmic positivity in bone marrow poietic cells. -
Gene Info — NCF2
Entrez GeneID
4688Protein Accession#
E9PHJ2Gene Name
NCF2
Gene Alias
FLJ93058, NCF-2, NOXA2, P67-PHOX, P67PHOX
Gene Description
neutrophil cytosolic factor 2
Gene Ontology
HyperlinkGene Summary
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein. [provided by RefSeq
Other Designations
67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|OTTHUMP00000033269|OTTHUMP00000033270|chronic granulomatous disease, autosomal 2|neutrophil cytosol factor 2|neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
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Interactome
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Pathway
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Disease
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