IARS polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of lane 1: A549 cell lysate, lane 2: H460 cell lysate and lane 3: H1703 cell lysate using IARS polyclonal antibody (Cat # PAB28520).
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant IARS.
Immunogen
Recombinant protein corresponding to amino acids 1074-1264 of human IARS.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of lane 1: A549 cell lysate, lane 2: H460 cell lysate and lane 3: H1703 cell lysate using IARS polyclonal antibody (Cat # PAB28520). -
Gene Info — IARS
Entrez GeneID
3376Gene Name
IARS
Gene Alias
FLJ20736, IARS1, ILRS, PRO0785
Gene Description
isoleucyl-tRNA synthetase
Omim ID
600709Gene Ontology
HyperlinkGene Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs. [provided by RefSeq
Other Designations
isoleucine tRNA ligase 1, cytoplasmic|isoleucine-tRNA synthetase
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Interactome
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Pathway
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Disease
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