PLA2G5 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PLA2G5 polyclonal antibody (Cat # PAB28512) in HL-60 cell line lysates (35ug/lane). PLA2G5 (arrow) was detected using the purified polyclonal antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human heart tissue with PLA2G5 polyclonal antibody (Cat # PAB28512) followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PLA2G5.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 103-132 at C-terminal region at human PLA2G5.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PLA2G5 polyclonal antibody (Cat # PAB28512) in HL-60 cell line lysates (35ug/lane). PLA2G5 (arrow) was detected using the purified polyclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human heart tissue with PLA2G5 polyclonal antibody (Cat # PAB28512) followed by peroxidase conjugation of the secondary antibody and DAB staining. -
Gene Info — PLA2G5
Entrez GeneID
5322Protein Accession#
P39877Gene Name
PLA2G5
Gene Alias
DKFZp686C2294, GV-PLA2, MGC46205, PLA2-10, hVPLA(2)
Gene Description
phospholipase A2, group V
Omim ID
601192Gene Ontology
HyperlinkGene Summary
This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq
Other Designations
Ca2+-dependent phospholipase A2|OTTHUMP00000002785|OTTHUMP00000044655|phosphatidylcholine 2-acylhydrolase
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Interactome
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Pathway
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Disease
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