HCN1 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of HCN1 polyclonal antibody (Cat # PAB28502) in Hela cell line lysates (35ug/lane). HCN1 (arrow) was detected using the purified polyclonal antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain tissue with HCN1 polyclonal antibody (Cat # PAB28502) followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HCN1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 860-889 at C-terminal region at human HCN1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HCN1 polyclonal antibody (Cat # PAB28502) in Hela cell line lysates (35ug/lane). HCN1 (arrow) was detected using the purified polyclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain tissue with HCN1 polyclonal antibody (Cat # PAB28502) followed by peroxidase conjugation of the secondary antibody and DAB staining. -
Gene Info — HCN1
Entrez GeneID
348980Protein Accession#
O60741Gene Name
HCN1
Gene Alias
BCNG-1, BCNG1, HAC-2
Gene Description
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
Omim ID
602780Gene Ontology
HyperlinkGene Summary
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain.[supplied by OMIM
Other Designations
brain cyclic nucleotide gated channel 1
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Interactome
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Disease
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Publication Reference
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Maternal Methyl-Enriched Diet Increases DNMT1, HCN1, and TH Gene Expression and Suppresses Absence Seizures and Comorbid Depression in Offspring of WAG/Rij Rats.
Karine Yu Sarkisova, Ekaterina A Fedosova, Alla B Shatskova, Margarita M Rudenok, Vera A Stanishevskaya, Petr A Slominsky.
Diagnostics (Basel, Switzerland) 2023 Jan; 13(3):398.
Application：WB-Ti, Rat, Rat cortex.
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Maternal Methyl-Enriched Diet Increases DNMT1, HCN1, and TH Gene Expression and Suppresses Absence Seizures and Comorbid Depression in Offspring of WAG/Rij Rats.
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