BRD8 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant BRD8.
Immunogen
Recombinant protein corresponding to amino acids of human BRD8
Sequence
EASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:50-1:200)
Immunofluorescence(1-4 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with BRD8 polyclonal antibody (Cat # PAB28491) shows strong nuclear positivity in cells of seminiferus ducts.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with BRD8 polyclonal antibody (Cat # PAB28491) at 1-4 ug/ml shows positivity in nucleus but not nucleoli & mitochondria. -
Gene Info — BRD8
Entrez GeneID
10902Gene Name
BRD8
Gene Alias
SMAP, SMAP2, p120
Gene Description
bromodomain containing 8
Omim ID
602848Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified. [provided by RefSeq
Other Designations
skeletal muscle abundant protein 2|thyroid hormone receptor coactivating protein
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Interactome
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Disease
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